Recent reviews have investigated the ability of the gut microbiota to mediate the effects of cannabinoids, including their metabolism and distribution throughout the body [13,14,15,16]
If it occurs, it is usually mild and responds well to basic dietary modifications alone
Pharmacists should also ensure that patients are not taking any medicines that can adversely affect the liver, check for any potential interactions and monitor the pharmacological therapy, as adverse effects of copper chelation can potentially worsen symptoms[6]
An intervention study in 57 healthy adults who were fed choline-deficient diets under controlled conditions found that 77% of men, 80% of postmenopausal women, and 44% of premenopausal women developed fatty liver, liver damage, and/or muscle damage (17)
The 2024 systematic review in the American Journal of Clinical Dermatology found most retinoin alternatives had comparable or slightly lower efficacy but better tolerability profiles
280 explored the role of GO in the oxidation of hydroquinone